In a new study, significant changes in erythrocyte sedimentation rate were observed in patients following a Mediterranean-like diet

Rheumatoid arthritis

Having a Mediterranean-like diet with anti-inflammatory foods may reduce systemic inflammation in patients with rheumatoid arthritis, according to an article published in the Journal of Nutrition.

The crossover study included 50 patients with a mean body mass index of 27 kg/m² and a mean age of 63 years. The participants were randomly assigned to start with a 10-week portfolio diet of proposed anti-inflammatory foods or a control diet resembling a Western diet, with a 4-month washout period in between, before starting on the other diet. The researchers evaluated markers of inflammation among participants on stable medication.

The results showed that there were no significant changes in levels of erythrocyte sedimentation rate (ESR) and C-reactive protein in the group as a whole. However, among participants who reported high compliance (n=29), there were significant changes in the ESR during the intervention diet period compared with the control diet period.

During the intervention diet period, there was also a reduction in other biomarkers related to inflammation, such as C-X-C motif chemokine ligand 1 (CXCL1), CXCL5, CXCL6, and tumour necrosis factor ligand superfamily member 14. However, these findings still need to be evaluated regarding their clinical relevance, the authors say.

This article originally appeared on Univadis, part of the Medscape Professional Network.

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