Venous thromboembolic diseases: diagnosis, management and thrombophilia testing

National Institute for Health and Care Excellence

Venous thromboembolic diseases cover a spectrum ranging from asymptomatic calf vein thrombosis to symptomatic deep vein thrombosis (DVT). They can be fatal if they lead to pulmonary embolism. Non‑fatal venous thromboembolism (VTE) can cause serious long-term conditions such as post‑thrombotic syndrome.

Major risk factors for VTE include a history of DVT, age over 60 years, surgery, obesity, prolonged travel, acute medical illness, cancer, immobility, and pregnancy.

This Guidelines summary covers diagnosis and pharmacological interventions, and includes a minor update on elastic graduated compression stockings.

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