Fertility problems: assessment and treatment

National Institute for Health and Care Excellence


It is estimated that infertility affects 1 in 7 heterosexual couples in the UK. The main causes of infertility in the UK include ovulatory disorders, and factors in the male causing infertility. In about 40% of cases, disorders are found in both the man and the woman. Uterine or endometrial factors, gamete or embryo defects, and pelvic conditions such as endometriosis may also play a role.

Given the range of causes of fertility problems, the provision of appropriate investigations is critical. These investigations include semen analysis; assessment of ovulation, tubal damage and uterine abnormalities; and screening for infections such as chlamydia trachomatis and susceptibility to rubella.

This Guidelines summary provides recommendations on psychological effects of fertility problems, and investigation of fertility problems and management strategies.


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