Coeliac disease: recognition, assessment and management

National Institute for Health and Care Excellence

It is estimated that 1 in 100 people are affected by coeliac disease. This condition can present with a wide range of clinical features, both gastrointestinal (such as indigestion, diarrhoea, abdominal pain, bloating, distension, or constipation) and non‑gastrointestinal (such as fatigue, dermatitis herpetiformis, anaemia, osteoporosis, reproductive problems, neuropathy, ataxia, or delayed puberty). The complications of coeliac disease (which may or may not be present at diagnosis) can include osteoporosis, ulcerative jejunitis, malignancy (intestinal lymphoma), functional hyposplenism, vitamin D deficiency, and iron deficiency.

This Guidelines summary covers the recognition, referral, and monitoring of people with coeliac disease.

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