This summary outlines risk factors and recommendations associated with fragility fractures and a treatment pathway for postmenopausal women from risk factors to pharmacological treatment. For further information, refer to the full guideline.
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Table 1: Risk factors associated with fragility fracture which should prompt consideration of fracture-risk assessment
|Risk category||Causative factor|
|Modifiable risk factors||
Table 2: Recommendations associated with modifiable risk factors for fragility fractures
|Risk category||Affected group||Recommendation|
|Alcohol||People who consume more than 3.5 units per day of alcohol||Reduce alcohol intake to nationally recommended levels (<14 units per week)|
|Smoking||All smokers||Stop smoking|
|Weight||People with low BMI (<20kg/m2)||Achieve and maintain a BMI level of 20–25 kg/m2|
|Coexisting diseases||People with conditions that predispose to osteoporosis (see Table 1)||Where possible treat coexisting disease|
|Drug treatments||People taking drugs that predispose to osteoporosis (see Table 1)||Where possible reduce or stop drug therapy|
Algorithm 1: Pathway from risk factors to pharmacological treatment selection in postmenopausal women
Want to learn more about this guideline?
Read the related Guidelines in Practice article
Scottish Intercollegiate Guideline Network. Management of osteoporosis and the prevention of fragility fractures. Edinburgh: SIGN; 2015. (SIGN Guideline No. 142). Available at: www.sign.ac.uk/our-guidelines/management-of-osteoporosis-and-the-prevention-of-fragility-fractures
Published date: August 2015.
Last updated: June 2020.