Meningococcal disease can affect all age groups, but the highest rates of disease are in children under 5 years of age, with the peak incidence in those under 1 year of age. There is a second peak in incidence in young adolescents aged 15–19 years. This Guidelines for Nurses summary gives a clear summary of Public Health England's updated guideline on the meningococcal ACWY immunisation programme for adolescents.