Guidelines for the treatment of actinic keratosis

International League of Dermatological Societies in cooperation with the European Dermatology Forum

Actinic keratoses (AKs) typically develop on areas of chronic sun exposed skin, presenting as scaly or keratotic patches, papules, or plaques on an erythematous base. Actinic keratoses are the most common skin lesions and have the potential to progress to invasive skin cancer. Risk factors for the development of AKs include advanced age, male gender, cumulative sun exposure, and fair skin type.


Actinic keratoses may occur as single lesions, multiple lesions, or in the context of field cancerisation. Differential therapeutic strategies for the treatment of these distinguishable subgroups of patients are necessary for adequate patient care.


This Guidelines summary covers presentation, diagnosis, and includes a table that gives an overview of treatment recommendations.

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