Neuropathic pain in adults: pharmacological management in non-specialist settings

National Institute for Health and Care Excellence


Key principles of care

  • When agreeing a treatment plan with the person, take into account their concerns and expectations, and discuss:
    • the severity of the pain, and its impact on lifestyle, daily activities (including sleep disturbance) and participation*
    • the underlying cause of the pain and whether this condition has deteriorated
    • why a particular pharmacological treatment is being offered
    • the benefits and possible adverse effects of pharmacological treatments, taking into account any physical or psychological problems, and concurrent medications
    • the importance of dosage titration and the titration process, providing the person with individualised information and advice
    • coping strategies for pain and for possible adverse effects of treatment
    • non-pharmacological treatments, for example, physical and psychological therapies (which may be offered through a rehabilitation service) and surgery (which may be offered through specialist services)
    • for more information about involving people in decisions and supporting adherence, see Medicines adherence (NICE clinical guideline 76)

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