Motor neurone disease: assessment and management

National Institute for Health and Care Excellence

Motor neurone disease (MND) is a neurodegenerative condition affecting the brain and spinal cord. It is characterised by the degeneration of primarily motor neurones, leading to muscle weakness. It is estimated that 4000 people are living with MND in England and Wales at any one time, occurring mostly in adults aged 55–79 years. Without a cure for the condition, care focusses mainly on the maintenance of a patient’s functional abilities, allowing them to live as full a life as possible.

This Guidelines summary provides recommendations on recognition and referral, information and support at diagnosis, cognitive assessments, prognostic factors, and organisation of care.

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