Familial hypercholesterolaemia: identification and management
National Institute for Health and Care Excellence
The prevalence of heterozygous familial hypercholesterolaemia (FH) in the UK population is estimated to be 1 in 500, which means that approximately 110,000 people are affected. The elevated serum cholesterol concentration that characterises heterozygous FH leads to a greater than 50% risk of coronary heart disease in men by the age of 50 years, and at least 30% in women by the age of 60 years, if left untreated.
This Guidelines summary covers diagnosis, identifying people with FH using cascade testing, and management