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Guideline on the treatment of acne
European Dermatology Forum
Clinical features and variants
open comedones (blackheads)
closed comedones (whiteheads)
Comedones frequently have a mid-facial distribution in childhood and, when evident early in the course of the disease, this pattern is indicative of poor prognosis
Mixture of non-inflammatory and inflammatory lesions
Superficial inflammatory lesions include papules and pustules (5 mm or less in diameter). These may evolve into deep pustules or nodules in more severe disease. Inflammatory macules represent regressing lesions that may persist for many weeks and contribute markedly to the general inflammatory appearance
Management of asthma in adults over 65 years of age
Development group: Gruffydd-Jones, McArthur, Murphy, Russell & Wise. This management algorithm was developed by a multidisciplinary expert panel: Gruffydd-Jones K et al with the support of a grant from Teva UK Limited.